Supersaturation mechanism of drugs from solid dispersions with enteric coating agents.
نویسندگان
چکیده
phenomena from solid dispersions with enteric coating agents in JP XI 2nd fluid(pH 6.8). Nifedipine,griseofulvin and spironolactone were used as drugs.The rate of crystallization of all drugs was remarkably inhibited by the presence of CMEC.It was found that the inhibition was not due to solubilization of the drugs by CMEC. The crystallization kinetics from supersaturated solutions suggested that the process of crystal
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 36 12 شماره
صفحات -
تاریخ انتشار 1988